45 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
Diagnosis of ascites ... syndrome, Massive liver ... albumin #gradient #hepatology ... #differential # ... diagnosis #algorithm
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic ... liver disease ( ... #Differential # ... Diagnosis #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
value = (ALT + ULN ... phosphatase + ULN ... Transaminitis #diagnosis ... #differential # ... hepatology
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
either made in the liver ... or not by the liver ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG ... Interpretation #Differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... AST/ALT (5-10x ULN ... infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... Diagnosis Algorithm ... disease • Acute liver ... #Differential # ... #Hepatology #causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... Others #LFTs #Hepatology ... #Diagnosis #Algorithm
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Acute fatty liver ... #Causes #diagnosis ... #differential # ... hepatology #SAAG
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
(HPS) HPS-differential ... Pulmonary vasculature ... Patients with liver ... Syndrome #HPS #hepatology ... #pulmonary #diagnosis
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis
Spontaneous Bacterial Peritonitis
 • Cirrhosis (high SAAG)
glucose < 50, LDH ULN ... at least 2): 1) Clinical ... Secondary #Peritoneal #diagnosis ... #differential # ... ascites