18 results
General approach to AKI - Checklist

Urine electrolytes & FENa - Previously, it was believed that urine
General approach to AKI ... sodium excretion ... fractional excretion of sodium ... @PulmCrit #AKI ... AcuteKidneyInjury #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI ... Workup Algorithm ... osmolarity If cause of AKI ... Kidney #Injury #AKI ... #Workup #Algorithm
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
volume-based algorithm Urine ... : SIADH, Renal Sodium ... Renal Losses (AKI ... diagnosis #table #sodium ... #nephrology
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Sodium Theophilus ... Kidney Injury (AKI ... sodium < 20 mEq ... sodium > 40 mEq ... #UNa #casts #glucosuria
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Neurological event 2) Sodium ... → Increased urine ... SaltWasting #SIADH #Pathophysiology ... #diagnosis #nephrology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... PROBLEM ~80% of AKI ... IMPROVEMENT If the urine ... LorinskyMD #AKI ... KidneyInjury #simplified #workup
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) Check Urine ... Differential #Diagnosis #Workup ... #Algorithm #nephrology ... #sodium
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Bartter syndrome, Gitelman ... Urine chloride is ... sodium is typically ... the excretion of sodium ... #Algorithm #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Hypocalciuria (spot urine ... Syndrome #diagnosis #nephrology ... #management #pathophysiology