18 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
, holster sign, ... anti-synthetase syndrome ... Can also see mechanics ... after 2 years of treatment ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... hyperthermia crisis (late sign ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... Myasthenia #Gravis #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and ... high WBC count cause ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
some time, let’s see ... about secondary causes ... you’ll do a good workup ... always a good idea ... #Algorithm #workup
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... microglobulin Treatment ... #workup #oncology ... #hematology