21 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... life-threatening • Treatment ... lupus #Systemic #Erythematosus ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Systemic Lupus Erythematosus ... Non-autoimmune rheumatologic ... pain • Swan neck/Ulnar ... • Malar rash - spares ... #Diagnosis #Rheumatology
Boxer's Fracture - ED Management
Be sure to assess for wounds in patients with fractures of the
Fracture - ED Management ... prophylactic antibiotic treatment ... hematoma block or ulnar ... nerve block), immobilize ... object) • Splint: Ulnar
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... systemic lupus erythematosus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
• Weakness: Starts ... • Pain: Due to nerve ... Treatment: • Plasmapheresis ... Syndrome #diagnosis #management ... #treatment #neurology
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
for aggressive treatment ... In short, best outcomes ... #Management #Neurology ... #CriticalCare #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Systemic Lupus Erythematosus ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management