27 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... thickening Signs and Symptoms ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Molluscum Contagiosum 
Clinical 
 • Most common in school-age children 
 • Transmitted by direct contact
• Painless, no systemic ... symptoms • Typically ... extremities • Spares ... #Contagiosum #Diagnosis ... #Clinical #Management
Indolent Systemic Mastocytosis (ISM)

 • Introduction and Diagnosis
 • Diagnostic Algorithm and Risk Stratification
 • Symptoms
Indolent Systemic ... Stratification • Symptoms ... and Symptom Management ... @ZhuoerXie #Systemic ... #SM #Indolent #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Disease, PRES Pathophysiology ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... Clinical Signs/Symptoms ... Systemic glucorticoids ... Bullous #Pemphigoid #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Tuberculosis - Diagnosis ... and Management ... Clinical Signs/Symptoms ... decreased reflexes Pathophysiology ... Residency @CMC_IM #Potts
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... with lymphatic system ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... them, but urgent rheumatology ... absence of visual symptoms ... Temporal #Signs #Symptoms ... #Diagnosis #Management