12 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Algorithm - Diabetes Insipidus ... & desmopressin test ... Management #Algorithm #Sodium ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Hypernatremia - Differential ... Central diabetes insipidus ... Hypernatremia #Differential ... Diagnosis #Causes #nephrology ... #sodium #high
Diabetes Insipidus - Diagnosis Algorithm
Tests:
 • Osmolality, Urine AND/OR
 • Osmolality, Serum or Plasma AND
 •
Diabetes Insipidus ... Diagnosis Algorithm Tests ... Plasma AND • Sodium ... Diagnosis #Algorithm #nephrology ... #differential
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
of Polyuria - Differential ... Water Deprivation Test ... Water Deprivation Test ... #Polyuria #Nephrology ... #Differential #
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Hypernatremia - Differential ... water loss, Serum Sodium ... kg • Diabetes Insipidus ... Hypernatremia #Nephrology ... #Differential #
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... Euvolemic: Diabetes insipidus ... Hypernatremia #Differential ... Workup #Algorithm #nephrology ... #sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... Nephrogenic diabetes insipidus ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Hypernatremia - Differential ... The differential ... , Dehydration: neurologic ... post-obstructive 3) Diabetes Insipidus ... #sodium
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Medium and large ... Positive pathergy test ... is a skin prick test ... Behcet disease) Differential
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
Co-morbid diabetes insipidus ... Differential Diagnosis ... : Diabetes Insipidus ... Urine Osm, Serum Sodium ... , Urine Sodium