27 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... history Step #2 ... & desmopressin test ... Management #Algorithm #Sodium ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Hypernatremia - Differential ... Central diabetes insipidus ... Hypernatremia #Differential ... Diagnosis #Causes #nephrology ... #sodium #high
Diabetes Insipidus - Diagnosis Algorithm
Tests:
 • Osmolality, Urine AND/OR
 • Osmolality, Serum or Plasma AND
 •
Diabetes Insipidus ... Diagnosis Algorithm Tests ... Plasma AND • Sodium ... Osmolality, Urine 1-2 ... #differential
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... Nephrogenic diabetes insipidus ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... renal mechanism 2) ... Euvolemic: Diabetes insipidus ... Workup #Algorithm #nephrology ... #sodium
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
of Polyuria - Differential ... Water Deprivation Test ... Water Deprivation Test ... #Polyuria #Nephrology ... #Differential #
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Hypernatremia - Differential ... water loss, Serum Sodium ... kg • Diabetes Insipidus ... Hypernatremia #Nephrology ... #Differential #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Serum Osmolarity 2) ... Osmolarity 3) Urine Sodium ... Diagnosis #Algorithm #nephrology ... #sodium #low #uricacid
1 Minute Neuro Hand Examination - "Check your Six" Mnemonic

A simple way to test the peripheral
simple way to test ... salute- median/ulnar ... ) 2) OK sign (anterior ... radial), Scissors (Ulnar ... bobvarkey #Minute #Neurology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of Diabetes Insipidus ... neurogenic diabetes insipidus ... mutations in AQP-2 ... Classification #Types #Nephrology ... #Diagnosis #Differential