22 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... of hip (rare), Arthritis ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... Clinical Domains ... • Arthritis domain ... Criteria #SLE #Systemic ... #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Diagnostic Criteria - Systemic ... Clinical and Immunologic ... Criteria CLINICAL ... Direct Coombs’ test ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... Fever is the main clinical ... lupus erythematosus ... Liver function tests ... #Rheumatology
Ulnar Compression Test - Ulnar Tunnel Syndrome

The ulnar compression test evaluates for ulnar tunnel syndrome.
Provide direct
Test - Ulnar Tunnel ... compression test ... tunnel or Guyon's canal ... Tunnel #Syndrome #wrist ... #PhysicalExam #clinical
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... pain • Swan neck/Ulnar ... #Diagnosis #Rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... small joints (wrists ... boggy" joints, esp carpal ... Boutonniere's ulnar ... deviation, etc • Systemic
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology