42 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... distal to elbows/wrists ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... Evolution: Chronic disease ... #rheumatology
Common Hand Fractures on X-Ray
Mallet finger - injury to the lateral extensor slips
Boutonniere deformity - injury
thumb injury to ulnar ... Kienboch disease ... Fractures #XRay #Radiology ... #Wrist #differential ... #diagnosis
Galeazzi Fracture 
Fracture of distal radial shaft with distal radial-ulnar joint disruption. Remember “MUGR” to recall
swollen forearm and wrist ... pronation and at wrist ... Radial #Distal #Radiology ... #XRay #Diagnosis ... #Management #Orthopedics
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Differential Diaqnoses ... solid cancers • Systemic ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... • MCTD (SLE/systemic ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
distal to distal ulna ... , pain with wrist ... distal radius or ulna ... #Carpal #Radiology ... #XRay #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... of underlying disease ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... small joints (wrists ... Boutonniere's ulnar ... deviation, etc • Systemic ... signs #symptoms #diagnosis
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... female, asian • Systemic ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology