20 results
diagnosis differential liver management algorithm classification causes lfts transaminitis criticalcare gastroenterology hepatitis acute druginduced elevation function interpretation tests acidosis aclf
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... Injury #Medications ... #LiverInjury #Hepatology ... Pharmacology #Causes #DILI
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 Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Drug-induced Liver Injury ... Types: • Intrinsic ... dose dependent injury ... induced #Liver #Injury ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... involvement, Kidney injury ... non-essential drug/HDS treatments ... malignant biliary obstruction ... Diagnosis #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
(>1000): • DILI ... Drug-induced liver injury ... Ischemic Hepatopathy (shock ... Differential #Diagnosis #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
HELLP • Trauma: Shock ... thrombosis, Sinusoidal obstruction ... • Iatrogenic: DILI ... Diagnosis #causes #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Hepatic artery: Shock ... VZV • Trauma: Shock ... • Iatrogenic: DILI ... Intrahepatic - Obstruction ... diagnosis #algorithm #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
abnormality vs bone Bili ... - Direct (Obstructive ... Hepatocellular injury ... 2: Cholestatic injury ... Transaminitis #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... Acute biliary obstruction ... Hepatic Artery: Shock ... Intrahepatic • Obstructive ... Acute #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Shock Classification and Differential Diagnosis SHOCK • MAP <65, SBP <90, drop in SBP > 40 •
Shock Classification ... Differential Diagnosis SHOCK ... Medications, Spinal Cord Injury ... Myocarditis, Arrhythmia Obstructive ... Differential #Diagnosis #Types
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