14 results
Diagnosis and management of Polyarteritis Nodosa (PAN)

Chapel Hill 2012 definition: 
Necrotizing vasculitis ofmedium or small arteries
Necrotizing vasculitis ... glomerulonephritis or vasculitis ... 140 umol/L - GI ... PolyarteritisNodosa #Rheumatology ... #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Inflammatory Conditions: Rheumatologic ... , Vasculitides, ... post-splenectomy, Exercise, Allergic ... Diagnosis #Algorithm #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... • Blood loss: GI ... bleed, GU bleed ... Deficiency #Anemia #Differential ... Algorithm #ferritin #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... Allergies): - Allergic ... Rhinitis - Allergic ... Asthma Tugs (vasculitis ... Diagnosis #Causes #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... inflammation of the upper ... neuropathy - GI ... in extremities, upper ... #rheumatology #
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... Kaposi's sarcoma • Rheumatologic ... Autoimmune: ANCA-Assoc vasculitis ... Bevacizumab Mimics: • GI ... bleed: esophageal
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... manifest on the face, upper ... reticularis Differential ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... mononeuritis multiplex • GI ... inflammation of the upper ... Diagnosis #Rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Lymph nodes in upper ... Extranodal disease: GI ... involvement Differential ... Lymphomas • Other hematologic ... #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... • Eosinophilic GI ... #Tryptase #Differential ... #Diagnosis #hematology ... #allergy