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Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... namely, the many causes ... many non-hepatic causes ... - Inherited Urea ... of ammonia: - Urease
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Treat underlying cause ... : • Causes can ... administered • Can cause ... volume overload Urea ... into ammonium by urease-producing
Lower Urinary Tract Infections: Complications - Infection damages the urinary tract epithelium causing fibroblast proliferation and
Prostatitis - Urease-producing ... Klebsiella) degrade urea ... which may cause
UROLITHIASIS 80% of stones are composed of calcium oxalate or phosphate. Others include uric acid (9%),
elevated urine pH, & urease ... Urea breakdown yields ... These mutations cause ... PCN #calculus #urease
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treat underlying cause ... administered • This can cause ... Urea powder • Induces ... into ammonium by urease-producing ... effects: Thirst, Nausea
Polyuria - Differential Diagnosis Solute Diuresis • Na intake/saline • Glucosuria: Hyperglycemia, SGLT-2 inhibitors • Urea: Exogenous
inhibitors • Urea ... Differential #Diagnosis #Causes
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Urine Na/K/Cl/urea ... rhabdo/TLS) Causes ... Diagnosis #Algorithm #Causes
Causes of Polyuria - Differential Diagnosis Algorithm Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min) Osmotic
Causes of Polyuria ... • Increased urea ... Diagnosis #Algorithm #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
electrolytes, urea ... osmolarity If cause ... Diagnosis #nephrology #causes
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
electrolyte abnormality caused ... among the possible causes ... lower than 80% in cases ... Rise in blood urea ... causes the hyponatremia
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