21 results
An AAV5 vector with a functional factor VIII gene tested in men with hemophilia A #EBM
gene tested in men ... hemophilia A #EBM ... VisualAbstract #NEJM
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
post-infectious GN ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Differential #Diagnosis #Nephrology
Stage III Glomerulonephritis on Electron Microscopy
This image shows acellular scanning EM from a biopsy with membranous
acellular scanning EM ... more extensive GBM ... surface of reticular GBM ... glomerulonephritis #MGN ... #stage3 #GBM #ElectronMicroscopy
Stage II Membranous Glomerulonephritis on Electron Microscopy
This eyeSCANdy image shows acellular scanning EM of a glomerulus
acellular scanning EM ... appearance of GBM ... glomerulonephritis #MGN ... #stage2 #GBM #ElectronMicroscopy ... SEM #clinical #nephrology
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
Glomerulonephritis (GN ... cytoplasmic antibodies; GBM ... Glomerulonephritis #Algorithm #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... Mesangiocapillary GN ... , CFHR5 neph) MPGN ... immune deposits on EM ... #nephrology #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Vasculitis • GN ... : ANCA, Anti-GBM ... Differential #Diagnosis #nephrology
Jaw Clonus on Physical Exam

A 24-year-old man presented with progressive dysphagia, dysarthria, and weakness in his
A 24-year-old man ... PhysicalExam #Clinical #Video ... #ALS #Neurology ... #NEJM
Pyogenic Granuloma of the Conjunctiva - A 30-year-old man presented with a pedunculated lesion on his
A 30-year-old man ... Clinical #Ophth #EM ... #Conjunctival #NEJM
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Membranoproliferative GN ... proliferative • Anti-GBM ... Post-infectious GN ... #Proteinuria #Nephrology