10 results
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... fasciculations. ... clinically characterized ... clinical findings ... positive Babinski reflex
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
and multiple spinal ... - Causes progressive ... Increased Jaw Jerk reflex ... BULBAR: Tongue fasciculations ... cervical and thoracic spine
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Cord Causes: 1 ... reflexes: Areflexia ... UMN Symptoms ... differential #algorithm
Hoffman's sign. Even in this specific case, accompanied by a clonus outline (rhythmic contractions). The median
this specific case ... pathway and the spinal ... Hoffmanns #Sign #Reflex ... #Positive #Abnormal ... #clinical #video
Causes of Dysarthria - Differential Diagnosis Algorithm
Lower Motor Neuron - Slow, Low Volume, Breathy Speech, Tongue
Causes of Dysarthria ... Facial Atrophy Fasciculations ... hyperactive gag reflex ... and Pitch • Spinal-Cerebellar ... #Causes
Tongue Fasciculations in Kennedy's Disease

A man in his 40’s with progressive nasal twang, dysphagia and weakness
Tongue Fasciculations ... shows a pectoral crease ... Final Dx- Kennedy ... expectancy is normal ... Kennedys #Disease #clinical
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... electrolytes, urea ... investigations depending on clinical ... Differential #Diagnosis #nephrology ... #causes
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Spasticity - Reflexes ... Sjogren's • CSF: - Abnormal ... • Infectious causes ... diagnosis #management #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... depressed deep tendon reflexes ... protein with a normal ... - Of note, normal
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Clinical ... Decreased / Absent Reflexes ... CSF PROTEIN - NORMAL ... of intrathecal spinal