15 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Gitelman syndrome ... from Bartter syndrome ... • Urine Chloride ... #syndrome #Bartter ... #Algorithm #nephrology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Proximal tubule Bartter ... tubule #Liddle ... #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis
Chloride depletion syndromes
 • Gastrointestinal losses
    -
Differential Diagnosis Chloride ... furosemide) - Bartter ... Gitelman syndrome ... • Liddle syndrome ... • Severe potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Low Aldosterone: Liddle's ... thiazide diuretics, Bartter ... syndrome, Gitelman ... #causes #potassium ... #low #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... , Liddle syndrome ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... , Liddle syndrome ... #Nephrology #Causes
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
glycyrrhizic acid, Liddle's ... h - Diuretics, Bartter's ... syndrome, Gitelman's ... #nephrology #causes ... #low #potassium
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
deficiency • Liddle ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... other • Severe potassium ... Diagnosis #Causes #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... mineralocorticoid excess, Liddle ... Mg2+ deficiency, Bartter ... syndrome, Gitelman ... #diagnosis #nephrology