23 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... Hypokalemia Metabolic alkalosis ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... Differential Diagnosis Algorithm ... , Gitelman Syndrome ... Primary #Metabolic #Alkalosis ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... , Gitelman syndrom ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... Differential Diagnosis Algorithm ... , Gitelman Syndrome ... Differential #Diagnosis #Algorithm ... #Nephrology #Causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... as arrhythmias and ... - Metabolic Alkalosis ... , Gitelman syndrome ... #nephrology #low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Hypokalemia (renal potassium ... Supplement: • Potassium ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... potassium acid ... #nephrology #differential
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Differential Diagnosis Algorithm ... Transcellular Shift: • Alkalosis ... • Refeeding syndrome ... #nephrology #low ... #potassium
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Differential Diagnosis Algorithm ... , Gitelman's syndrome ... Differential #Diagnosis #Algorithm ... #nephrology #causes ... #low #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... • Skin and/or ... , Gitelman's syndrome ... #causes #nephrology ... #potassium