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diagnosis management differential hyponatremia neurology siadh aids alkalosis associated bartter chloride dementia disorder epithelial fanconi hand hepatology hepatorenal hiv hrs
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Renal Tubular Defects ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... #Kidney #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Rhabdomyolysis Treatment ... #nephrology #management ... #pathophysiology
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
volume overload Urea ... promoting passive sodium ... Has many side effects ... #hyponatremia #nephrology ... #treatment
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... the excretion of sodium ... #nephrology #differential
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... promoting passive sodium ... • Major side effects ... #hyponatremia #nephrology ... #treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Pathophysiology ... Treatment: • ... others (botox, sodium ... Diagnosis #Management #treatment ... #neurology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Pathophysiology: ... • Urine sodium ... Treatment Overview ... #Hepatology #Nephrology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... barrier (BBB), and infects ... volume • Patchy areas ... The clinical syndrome ... Treatment: • HAART
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