10 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... , Gitelman syndrom ... #causes #potassium ... #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... , Gitelman's syndrome ... differential #diagnosis #algorithm ... #causes #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... , Gitelman's syndrome ... #Hypokalemia # ... #nephrology #causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... wasting from other causes ... , Gitelman syndrome ... #diagnosis #Algorithm ... differential #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... thiazide-sensitive sodium ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... , Gitelman syndrome ... the indicated causes ... the excretion of sodium ... #nephrology #differential
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... : Hypovolemia, Hypervolemia ... Cirrhosis, Nephrotic syndrome ... #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Osmoles, Increased Urate ... Tumor Lysis Syndrome ... IntercellularShift #Nephrology ... #Causes
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
- Differential Algorithm ... polydipsia • Hypervolemia ... Cirrhosis, Nephrotic Syndrome ... #diagnosis #causes ... #nephrology #sodium