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diagnosis differential algorithm hypokalemia potassium aids associated bartter causes common cvid dementia disorder epithelial fanconi gout hematology hiv hypogammaglobulinemia immunodeficiency
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Renal Tubular Defects ... tubule #Liddle ... #Bartter #Gitelman ... #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Normal Acid-Base: Low ... acidosis: Proximal and ... Aldosterone: Liddle's ... , Gitelman syndrom ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... ascending limb Gitelman ... convoluted tubule Liddle ... open time and number ... #Kidney #Nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
as arrhythmias and ... mineralocorticoid excess, Liddle's ... , Gitelman syndrome ... differential #potassium #nephrology ... #low
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... Monosodium urate ... • Metabolic syndrome ... predominance • Urate ... #Gout #Comparison
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... Can present in middle ... breast cancer ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... infects the CNS ... ARVs can have low ... The clinical syndrome ... with low CD4 counts
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