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diagnosis algorithm management neurology causes kidney phosphate treatment acidosis acute aki alkalosis chloride criticalcare defects epithelial heat heatstroke hp hypernatremia
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... - Differential ... Diagnosis Framework ... Rhabdomyolysis, Tumor lysis syndrome ... #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... - Differential ... Diagnosis Framework ... #Workup #phosphate ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... Diagnosis Workup ... , Cushing syndrome ... #Algorithm #nephrology ... #sodium
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... ratio 0.5%) Differential ... #nephrology #management ... #pathophysiology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... electrolytes, urea ... • Cardio-renal syndrome ... #Injury #AKI #Workup ... #Diagnosis #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... the excretion of sodium ... urine #Algorithm #nephrology ... #differential #
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Diagnosis Framework ... Ischemia, Compartment Syndrome ... Beta-Agonists, ↑ work ... toxic alcohols, Sodium
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... dystrophies Work ... #Weakness #Differential ... #Diagnosis #neurology
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