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diagnosis management oncology hepatology neurology aids associated barre cancer dementia differential differentiation disorder enzymes gbs guillain hand hepatorenal hiv hrs
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... #APML #diagnosis ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... Intracellular Urate ... #Leukemia #Hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
JAK2 mutation OR Abnormally ... When present, symptoms ... transformation into AML ... • Treatment algorithms ... Summary #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
70 years Symptoms ... transformation to AML ... low and appear abnormal ... progression to AML ... #diagnosis #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... suspicious clinical symptoms ... presence of metabolic syndrome ... Areas of diagnostic ... #Algorithm #Hepatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
1) 4) Average age ... survival is 93-95% Pathophysiology ... mediators such as ... Self-limiting, chronic but stable ... ), liver (pain/abnormal
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... • Depressive symptoms ... volume • Patchy areas ... The clinical syndrome ... dementia #AIDS #Neurology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Pathophysiology: ... • Normal kidney ... be substituted as ... #Hepatology #Nephrology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... as either demyelinating ... Guillain #Barre #Syndrome
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment algorithm ... Myelodysplastic syndromes ... disease-associated symptoms ... #algorithm #hematology
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