6 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Renal Tubular Defects ... Proximal tubule Bartter ... #Fanconi #Bartter ... #Pathophysiology ... #Nephrology
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
sedative use, CNS ... /muscular disorders ... Barter, or Gitelman ... Syndrome Unremarkable ... metabolic #alkalosis #algorithm
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... acid transporter Bartter ... ascending limb Gitelman ... #Kidney #Nephrology ... #Differential #Table
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... the blood-brain barrier ... (BBB), and infects ... the CNS in the ... The clinical syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... , Seizure disorders ... Disease, PRES Pathophysiology ... or blood-brain barrier
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Suspect in movement disorders ... Symptoms: AMS, motor deficits ... periventricular areas ... subcortical white matter ... InfectiousDiseases #Neurology