15 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Defects Fanconi ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Pathophysiology ... #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Transient renal tubular ... - Gitelman ... Genetic defects ... Hypomagnesemia #Differential ... Low #Magnesium #Table
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
) - Differential ... Diagnosis Algorithm ... • Hepatorenal syndromes ... Shock Acute Tubular ... #KidneyInjury #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Workup Algorithm ... electrolytes, urea ... • Cardio-renal syndrome ... #Workup #Algorithm ... Diagnosis #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Hypokalemia - Differential ... Diagnosis Algorithm ... hypokalemia • Renal tubular ... , Gitelman's syndrome ... #causes #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Diagnosis Algorithm ... Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... ratio 0.5%) Differential ... , Renal tubular ... #nephrology #management ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Metabolic Alkalosis: Differential ... diuretics after renal tubule ... reabsorptive defect ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology