11 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis - Urinary ... Chloride Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... #Algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... secreting tumor, Primary ... , Gitelman syndrom ... Differential #Diagnosis #Algorithm ... potassium #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... starts by measuring urinary ... • Skin and/or ... , Gitelman's syndrome ... #causes #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
inhibitors - Primary ... Medications - Loop and ... - Gitelman ... Genetic defects ... Low #Magnesium #Table
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
contracted: urine chloride ... > 20 meq/L • Primary ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... Increased open time and ... #Kidney #Nephrology ... #Differential #Table
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... as arrhythmias and ... mEq/g suggests urinary ... , Gitelman syndrome ... differential #potassium #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... - Bartter - Gitelman ... • Fatigue Chloride ... #Pathophysiology ... #Nephrology #Chloride
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... urine microscopy / urinary ... calcium Optional: urinary ... electrolytes, urea ... Differential #Diagnosis #nephrology