29 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Proximal tubule Bartter ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... thiazide diuretics, Bartter ... syndrome, Gitelman ... #Hypokalemia #Differential ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Familial: Bartter ... syndrome and Gitelman ... syndrome, Isolated ... diagnosis #causes #nephrology ... #magnesium #low
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... h - Diuretics, Bartter's ... syndrome, Gitelman's ... #Differential # ... Diagnosis #Algorithm #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Low-normal EABV ... Mg2+ deficiency, Bartter ... syndrome, Gitelman ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... alkalosis • Normal or low ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... Diagnosis Algorithm Low ... tubular acidosis • Gitelman's ... syndromeBartter's ... syndrome Extrarenal
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
acid transporter Bartter ... ascending limb Gitelman ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table