11 results
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... autosomal dominant kidney ... dr_missyhanna #Gitelman ... #Syndrome #Diagnosis ... #Workup #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Gitelman ... syndrome - ... Differential #Diagnosis #Low ... #Magnesium #Table ... Classification #Causes #Workup
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... ascending limb Gitelman ... Inherited #Defects #Kidney ... #Nephrology #Diagnosis ... #Differential #Table
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
↑ Aldosterone: Kidney ... Low-normal EABV ... , Low Plasma HCO3 ... , Gitelman syndrome ... algorithm #diagnosis #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Appropriately Low ... Kidney Phosphate ... Inappropriately High Kidney ... Diagnosis #Algorithm #nephrology ... #phosphorus #workup
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... consumption • Low ... , Gitelman syndrome ... differential #potassium #nephrology ... #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Kidney ... alkalosis • Normal/low ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... urine #Algorithm #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... electrolytes, urea ... #Injury #AKI #Workup ... Differential #Diagnosis #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Decreased Intake: • Low ... - Bartter - Gitelman ... unloading • Kidney ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... alkalosis • Normal or low ... #nephrology #management ... #pathophysiology