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diagnosis management neurology rheumatology aids associated cerebritis dementia differential disorder erythematosus hand hepatology hepatorenal hiv hrs leukemia lupus myelitis neurocognitive
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #CNS #neurology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... • Caused by splanchnic ... Pathophysiology: ... Treatment Overview ... #Hepatology #Nephrology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... and infects the CNS ... mononuclear cells in the CNS ... The clinical syndrome ... Treatment: • HAART
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... : CNS manifestations ... • Tumor lysis syndrome ... Intracellular Urate ... #Leukemia #Hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Evaluate for NMO, SLE ... Disorders: - SLE ... Transverse Myelitis Treatment
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... cell lymphoma Pathophysiology ... histopathologic changes in LNs ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology
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