32 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Precipitation => • Urate ... Nephropathy (low urine ... #UricAcid
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
ADH promotes Urea ... Osmolarity 2) Urine ... Osmolarity 3) Urine ... #nephrology #sodium ... #low #uricacid
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... dysmorphic RBCs in urine ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... • Urine Chloride ... • Urine Ca/Cr ... #Bartter #Algorithm ... #nephrology #hypokalemia
Nephritic nephrotic algorithm. #kidney #Nephritic #Nephrotic #Syndrome #Comparison #Algorithm #Nephrology #Diagnosis
Nephritic nephrotic algorithm ... Nephritic #Nephrotic #Syndrome ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... → Increased urine ... SaltWasting #SIADH #Pathophysiology ... #diagnosis #nephrology ... #hyponatremia #comparison
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... hyperaldosteronism • Low Urine ... (late) • High Urine ... Differential #Diagnosis #Algorithm ... #nephrology
Urine Microscopy Crystals
Uric Acid crystals:
 - Formation promoted by acidic urine
 - Seen in tumor lysis
Urine Microscopy ... promoted by acidic urine ... in tumor lysis syndrome ... Seen in UTIs by urease-producing ... Microscopy #Crystals #comparison
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... hyperaldosteronism • Low Urine ... (late) • High Urine ... Differential #Diagnosis #Algorithm ... #Nephrology #Causes
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The last step in purine ... animals, the enzyme uricase ... Uricase is not present ... #UricAcid #Homeostasis ... #Gout #Pathophysiology