72 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Precipitation => • Urate ... Nephropathy (low urine ... nephropathy (high urine
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
1ml blood/liter urine ... disease - Alport syndrome ... pain hematuria syndrome ... • Nutcracker syndrome ... #urology #nephrology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... volume overload Urea ... into ammonium by urease-producing ... Saline: • If Urine ... #hyponatremia #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
electrolytes, urea ... osmolarity If cause ... • Cardio-renal syndrome ... Differential #Diagnosis #nephrology ... #causes
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Proteinuria (Negative urine ... • Fanconi's syndrome ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... (blue diaper syndrome ... Bag Syndrome - ... UTI caused by (Proteus ... Differential #Diagnosis #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... Diagnosis #Algorithm #Nephrology ... #Causes
Distal Renal Tubular Acidosis (RTA)  Type 1 

Totally scuppers the kidney's acidification mechanism. Will be
diagnosis with direct urine ... Failure to acidify urine ... Distal #Diagnosis #Management ... #Nephrology #Causes