26 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndromeUrine ... Chloride • Urine ... krithicism #Gitelman ... #Algorithm #nephrology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Syndrome: Distal ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... RBC casts in urine ... Proteinuria often ... Massive proteinuria ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... nephrotic/nephritic syndromes ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... • Fanconi's syndrome ... (Positive urine ... albuminuria) - Active urine ... #Nephrology #Differential
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... , Liddle syndrome ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... , Liddle syndrome ... Diagnosis #Algorithm #Nephrology
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
Urine Specific Gravity ... Gravity = Density of urine ... Dehydration • SIADH (syndrome ... Glycosuria • Proteinuria ... #differential #nephrology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Precipitation => • Urate ... Nephropathy (low urine ... nephropathy (high urine