30 results
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Role of Uric Acid ... inflammation #gout #uricacid ... pathophysiology #pharmacology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
• Lower uric ... Hyperparathyroidism • Diabetic ... Alcohol #gout #UricAcid ... endocrinology #causes
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Uric Acid Homeostasis ... metabolized to uric ... uricase converts uric ... #UricAcid #Homeostasis ... Pathophysiology #Pharmacology
TACROLIMUS - Side Effects Mnemonic

Tremor 
Alopecia 
Cardiovascular (HTN) 
Renal insufficiency 
Oncologic (Skin Cancer) 
Lipids (hyperlipidemia) 
Insulin
Insulin dependent diabetes ... Magnesium wasting Uric ... Seizures #Pharmacology
Causes of Hyperuricemia
Increased production
 • Solid-organ transplant
 • Tumor lysis syndrome
 • Rhabdomyolysis
 • Lesch Nyhan
Causes of Hyperuricemia ... lactic acid + uric ... degradation -> uric ... Hyperuricemia #Causes ... #UricAcid #diagnosis
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
weight of various classes ... of type-2 diabetes ... Weight Gain ++++ #diabetes ... weightgain #comparison #pharmacology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Systemic and Primary Causes ... Blood Glucose: • Diabetes ... renal failure/uremia ... Diagnosis #Algorithm #causes
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Medication Guide Classes ... insulin in Type 1 Diabetes ... monitors in Type 1 Diabetes ... #Medications #pharmacology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... kidney), which causes ... SGLT2 #Inhibitors #Pharmacology ... Medications #DM2 #Diabetes
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... e.g. diarrhea, nausea ... #Metformin #Pharmacology ... #Summary #DM2 #diabetes