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diagnosis hematology management hemophagocytic lymphohistiocytosis oncology syndrome activation aplastic autoinflammatory classification e1 enterocolitis hodgkins lymphoma macrophage mas nec neutropenic somatic
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... : ↑↑ ferritin, Anemia ... : • Fever • Splenomegaly ... Lymphohistiocytosis #diagnosis #hematology ... #criteria
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
Diagnostic criteria ... for Neutropenic ... 30mm length) • Fever ... 1min_idconsult #NEC #Neutropenic ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... with leukopenia, anemia ... Histopathologic criteria ... #Rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... antibiotics if neutropenic ... fever) Complications ... management #treatment #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Weight loss • Anemia ... Immune hemolytic anemia ... through Ann Arbor criteria ... classification #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009 At least three of the following: -
Lymphohistiocytosis (HLH ... ) Diagnostic Criteria ... following: - Fever ... @PulmCrit #HLH ... #Hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
disease, recurrent fevers ... Abnormalities: macrocytic anemia ... (MDS) Most met criteria ... Autoinflammatory #Somatic #rheumatology
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