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diagnosis hematology management hemophagocytic lymphohistiocytosis disease oncology activation adult adultonset aosd causes classification differential edema enterocolitis hodgkins lymphoma macrophage major
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... Society Criteria ... : • Fever • Splenomegaly ... Lymphohistiocytosis #diagnosis #hematology ... #criteria
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
Diagnostic criteria ... for Neutropenic ... 30mm length) • Fever ... 1min_idconsult #NEC #Neutropenic ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... • Adult-onset Still ... - Nonremitting fever ... Histopathologic criteria ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... • Clinical: fever ... • Familial HLH ... +, Adult-onset Still ... treatment #summary #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... 5 of the below criteria ... Minor criteria include ... #Adult #onset #Stills ... AOSD #diagnosis #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... : - Fever >= 39C ... with concomitant fever ... #AdultOnset #Stills ... #Major #Minor #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009 At least three of the following: -
Lymphohistiocytosis (HLH ... ) Diagnostic Criteria ... following: - Fever ... @PulmCrit #HLH ... #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... • Dyspnea • Fever ... rich classical HL ... through Ann Arbor criteria ... classification #hematology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
- Low-grade fever ... and diffuse Neurogenic ... capillaries • Criteria ... insufficiency, fever ... , chills, pruritus
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