25 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Urobilinogen • + urinary ... #Differential #Causes ... #Workup #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Extravascular Causes ... usually IgM) (e.g. primary ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia • Primary ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Reticulocytosis • Primary ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... iron deficiency, hemolysis ... Post-splenectomy Primary ... Differential #Diagnosis #Causes ... #hematology #secondary
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Production • Hemolysis ... Cholangiocarcinoma • Primary ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/Quantity: • Primary ... • Secondary Causes ... DIC/TTP/HUS - Hemolytic ... Differential #Diagnosis #hematology ... #rheumatology #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... biliary obstruction, Primary ... biliary cholangitis, Primary ... Diagnosis #Algorithm #hepatology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... include pain, primary ... SatyaPatelMD #SIADH #Management ... #hyponatremia #nephrology ... #treatment
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... EPO-independent (primary ... up EPO levels Primary ... Algorithm #workup #hematology