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diagnosis differential algorithm management microscopy clinical nephrotic syndrome treatment aki hematuria workup glomerular nephritic radiology renal glomerulonephritis granular nephritis neurology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... (Negative urine ... sediment - WBC/RBC casts ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
RBC casts in urine ... Proteinuria often ... but in severe cases ... Massive proteinuria ... #Nephrology #Diagnosis
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... glomerular bleeding (proteinuria ... , RBC casts, dysmorphic ... → Refer to Nephrology ... if cause not identified
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... on Urine Microscopy ... of mb granular casts ... Granular #MuddyBrown #Casts ... #Clinical #Nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... #Urine #Microscopy ... #nephrology #interpretation
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria and/or proteinuria ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• White cell casts ... infection • Hyaline casts ... disease • Granular casts ... key #diagnosis #nephrology ... #casts
Lipid Casts on Urine Microscopy Dr. Telma Lemos @TELMALEMOS10 #Lipid #Casts #Urine #Microscopy #clinical #fatty #nephrology
Lipid Casts on Urine ... TELMALEMOS10 #Lipid #Casts ... #Urine #Microscopy ... clinical #fatty #nephrology
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 Waxy Casts on Urine Microscopy Dr. Telma Lemos @TELMALEMOS10 #Waxy #Casts #Urine #Microscopy #clinical #nephrology
Waxy Casts on Urine ... TELMALEMOS10 #Waxy #Casts ... #Urine #Microscopy ... #clinical #nephrology
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 RBC Casts on Urine Microscopy Dr. Telma Lemos @TELMALEMOS10 #RBC #Casts #Urine #Microscopy #clinical #nephrology
RBC Casts on Urine ... TELMALEMOS10 #RBC #Casts ... #Urine #Microscopy ... #clinical #nephrology
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