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diagnosis algorithm differential nephrotic hematuria nephritic renal syndrome workup blood glomerulonephritis nephritis syndromes testing urology biopsy chronic ckd classification comparison
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • White cell casts ... • Granular casts ... key #diagnosis #nephrology ... #casts
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... #Diseases #Nephritic ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... sediment - WBC/RBC casts ... Minimal change disease ... #Nephrology #Differential
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... bleeding (proteinuria ... , RBC casts, dysmorphic ... → Refer to Nephrology ... if cause not identified
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
basement membrane disease ... hematuria: - RBC casts ... - Proteinuria ... disease Renal ... #urology #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... cell/white cell casts ... because nephritic urine ... Nephrocalcinosis causes ... #syndrome #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... RBCs and/or RBC casts ... • Thin GBM disease ... • Pauci-immune disease ... nephrotic range) proteinuria
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Atherosclerosis Glomerular ... (Proteinuria) ... Sterile pyuria, WBC casts ... KidneyDisease #Nephrology ... Diagnosis #Algorithm #Causes
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24- ... hour urine collection ... infections are common causes ... of glomerular disease ... nephrotic #nephritic #nephrology
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