27 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
- Nephritic and ... Nephrotic Syndromes ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Syndrome and Nephritic ... Red blood cell casts ... Red blood cell casts ... edgarvlermamd - Nephrology ... Comparison #Table #Nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... edgarvlermamd - Nephrology ... Microscopy #Diagnosis #Nephrology
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
HTN, Vasculitis Glomerular ... : • Nephrotic: ... Amyloidosis, MPGN • Nephritic ... Antibiotics, NSAIDs, Cast ... Renal #Disease #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... proteinuria, RBC casts ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... RBCs and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
• White cell casts ... infection • Hyaline casts ... disease • Granular casts ... key #diagnosis #nephrology ... #casts
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... > 500 mg/d • Nephritic ... dysmorphic RBCs, RBC casts ... , WBC casts) especially ... algorithm #sle #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation