14 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
- Pathophysiology ... Hypovolaemia → ADH ... → Increased urine ... #diagnosis #nephrology ... #hyponatremia #
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... treat underlying cause ... (CHF, cirrhosis ... , SSRIs) - SIADH ... Algorithm #diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Reduced GFR, AKI/CRF ... Hypo-osmolar urine ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Reduced GFR, AKI/CRF ... Hypo-osmolar urine ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... volume-based algorithm Urine ... restriction alone in SIADH ... Present (Uosm ≥100): SIADH ... table #sodium #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... vast majority of cases ... Measure urine osmolality ... volume status (EABV ... Treatment #management #nephrology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
lower than 80% in cases ... in blood urea causes ... #hyponatremia #ADH ... #Hypovolemia #EBV ... #potomania #SIADH
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... Saline: • If Urine ... antagonists: • Blocks ADH ... #Management #hyponatremia ... #nephrology #treatment
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Treat underlying cause ... 0.9% NS • If Urine ... vaptans) • Blocks ADH ... #Management #hyponatremia ... #nephrology #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... - HIV, CMV, EBV ... /constipation, hyponatremia ... management #treatment #neurology