11 results
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... kidney), which causes ... glucose in the urine ... excretion in the urine ... #Pharmacology #
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... not definitively cause ... #Pharmacology # ... Summary #DM2 #diabetes
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... Ketones in serum or urine ... Treatment involves ... therapy in severe cases ... Euglycemic #DKA #EDKA #Toxicity
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Medication Guide Classes ... Sulfonylurea, TZD, DPP-4 inhibitor ... α-glucosidase inhibitor ... #Medications #pharmacology ... #comparison #table
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint Inhibitor ... Toxicity Main ... Complications and Treatment ... #SideEffects #Table ... #Diagnosis #Pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Nephrogenic diabetes ... Kidney stones caused ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
vera, Licorice - Causes ... risk of digoxin toxicity ... increasing risk for toxicity ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
status and low urine ... the determined cause ... #table #foamed ... heartfailure #chf #criticalcare ... icu #clinical #pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... infusion, Calcineurin inhibitors ... lysis) ± Urine ... only if no clear cause ... Elimination (see Table
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
(folinic acid) treatment ... thymidylate and purine ... ineffective because MTX inhibits ... evidence of marrow toxicity ... #Management #Pharmacology