15 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
- Indications and ... Pharmacology Pharmacokinetics ... of Excretion: Urine ... diarrhea & abdominal pain ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... + Etiological Assessment ... • Clinical: fever ... Treatment: • ... #summary #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... , abdominal pain ... Urticaria #diagnosis #rheumatology ... #comparison #table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Dermatomyositis Clinical ... Weakness - Dark urine ... - Abdominal pain ... hour with goal urine
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... Clinical Features ... Rule out other causes ... lower jaw Treatment ... SAPHO #Syndrome #Rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
The assessment of ... low urine output ... the determined cause ... #table #foamed ... #pharmacology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... Relapsing-remitting course +++ Clinical ... paresthesia, abdominal pain ... hypoalbuminemia with no urine ... #rheumatology
Clinical Opioid Withdrawal Score (COWS)

Resting Pulse Rate: Record beats per minute after patient is sitting or
Clinical Opioid ... patient was having pain ... joints or muscles and ... last ½ hour • 2 - nausea ... Hospital Opioid Use Treatment