12 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... Haptoglobin Urine ... hemosiderin Urine ... #workup #diagnosis ... #hematology #hemolysis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... mimics, repeat testing ... nephrolithiasis • Symptoms ... #Algorithm #Workup
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... evaluation or workup ... for specific symptoms ... glucocorticoid treatment ... #Differential #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... #Differential #Diagnosis ... #Algorithm #workup ... #hematology #testing
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... Positive Coombs testing ... post infectious setting ... passage of red-brown urine ... #anemia #hematology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... disease 24-hour urine ... LDH - Assess for hemolysis ... #workup #diagnosis ... nephrotic #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... glomerular #disease #workup ... #diagnosis #initial ... #testing #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... 3 questions to work ... Measure urine osmolality ... up to 3x in the setting ... #nephrology #sodium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
injury, ischemia, hemolysis ... reabsorption) Workup ... Pseudohyperkalemia - hemolysis ... lysis) ± Urine ... #potassium #nephrology