15 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
recycles peripheral lactate ... Diagnosis of MALA ... gastrointestinal distress and acute ... kidney injury are ... also includes symptoms
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... Diagnosis Baseline ... clinical context and signs ... #Kidney #Injury ... #Diagnosis #nephrology
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Seizures Kidney ... Liver: Loss of metabolic ... lung injury, ... liver #failure #Signs ... #Symptoms #Diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Diagnosis Framework ... Heat stroke - Metabolic ... nephrotoxicity to kidney ... Isotonic fluid/Lactated ... causes #treatment #nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... UOP/weights - Urine ... #Diagnosis #Algorithm ... #Causes #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... impairment of cellular metabolism ... excretion (e.g., urine ... sweat) - its metabolism ... liver or renal injury
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Diagnosis Framework ... muscle, liver, and kidney ... : • Early acute ... associated with any symptoms
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Coltivirus Symptoms ... : • Acute meningeal ... signs (fever, nuchal ... established by CSF or urine ... #diagnosis #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Diagnosis Approach ... hypertension and signs ... kidney injury). ... hypokalemia and metabolic ... renal bruit or signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... Diagnosis Framework ... and signs below ... Toxic Metabolic: ... #neurology #differential