52 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Serum Osmolarity 2) ... Low Uric Acid → SIADH ... Rachel Stern MD #Hyponatremia ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Step 2. ... mmol/L - true hyponatremia ... renal failure #Hypernatremia ... #Nephrology
Hyponatremia - Differential Diagnosis and Evaluation Algorithm
In addition to edema and urine concentration, always consider urine
Hyponatremia - Differential ... when evaluating hyponatremia ... amzn.to/3rEtbK8 #Hyponatremia ... #Differential # ... #nephrology
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
True Hyponatremia ... Differential Algorithm ... and hypervolemic hyponatremia ... low in euvolemic hyponatremia ... #Nephrology
Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg)
Assess Volume Status,
Hypo-osmolar Hypotonic HypoNatremia ... Algorithm (Serum ... Na, Urine Osm ... #Hyponatremia ... #Nephrology #Differential
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... underlying cause (CHF ... , SSRIs) - SIADH ... UnremarkableLab #Hyponatremia ... #diagnosis #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... uric acid <4 • SIADH ... SatyaPatelMD #Volume #Hyponatremia ... #algorithm #diagnosis ... #sodium #low #nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Salt Wasting vs SIADH ... Neurological event 2) ... → Increased urine ... Pathophysiology #diagnosis #nephrology ... #hyponatremia #
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... Inappropriate - Consider: SIADH ... @NephroMD #hyponatremia ... #diagnosis #differential ... #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... Hypo-osmolar urine ... osmole intake #Hyponatremia ... #Nephrology #Differential