20 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... concentrating defect: • Diuretics ... • Osmotic diuresis ... Diagnosis #Causes #nephrology ... #sodium #high
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
intravenous; SGLT2‐I, sodium–glucose ... ultrafiltration; UO, urine ... #Diuretic #Diuresis ... #CHF #Algorithm ... #HeartFailure #Cardiology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Check Urine Osmolality ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... #Algorithm #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Urine Na+K / serum ... loss (diuretics ... deficiency, Post-AKI diuresis ... (AKI, Post-AKI diuresis ... #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Algorithm Hypertonic ... Urologic irrigants Hypotonic ... , Medications (diuretics ... #Algorithm #diagnosis ... #sodium #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
and Workup Step ... Repeat the sodium ... volume loss - diuretics ... HYPERVOLEMIC • CHF ... #Algorithm #Nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Algorithm Isotonic ... • Hypovolemia: Diuretics ... Alcohol MH/CCF ... diagnosis #causes #nephrology ... #sodium #low
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
water loss, Serum Sodium ... 145 mmol/L High Urine ... 300 mmol/kg • Hypertonic ... administration • Osmotic diuresis ... #Nephrology #Differential
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
Differential Diagnosis Algorithm ... /min) Osmotic Diuresis ... administration Hypertonic ... Primary polydipsia Hypotonic ... #Polyuria #Nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... ) Naturiesis → diuresis ... → Increased urine ... Pathophysiology #diagnosis #nephrology ... #hyponatremia #