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nephrology differential low table adh cancer comparison ebv hypernatremia hypotonic hypovolemia lazy oncology osmolality pathophysiology physiologic potomania raas saltwasting thiazides
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Cerebral Salt Wasting ... Neurological event 2) Sodium ... → Increased urine ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... Osmolarity 2) Urine ... Sodium 4) Serum ... Low Uric Acid → SIADH
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Based Approach to Hyponatremia ... Renal losses, Cerebral ... uric acid <4 • SIADH ... #algorithm #diagnosis ... #sodium #low #nephrology
Hyponatremia - Diagnostic Evaluation Algorithm Step 1: Consider whether Posm may actually be normal or elevated Step 2:
Hyponatremia - Diagnostic ... Evaluation Algorithm ... Check Uosm and/or Urine ... tests Step 5: If SIADH ... #Evaluation #Algorithm
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Algorithm Hypertonic ... OFF (UNa > 30): SIADH ... Reset osmostat, Cerebral ... #Algorithm #diagnosis ... #sodium #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Urine Na+K / serum ... Insufficiency, Cerebral ... #differential #diagnosis
A lazy man's classification of hyponatremia There are two possible approaches to the diagnosis of hyponatremia: .
serum osmolality, urine ... osmolality and urinary sodium ... the patient has SIADH ... or cerebral salt ... #Diagnosis #Hyponatremia
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... Diagnosis Algorithm ... , SSRIs) - SIADH ... #Algorithm #diagnosis ... #nephrology #sodium
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Diagnosis by Mechanism ... ADH secretion (SIADH ... osmostat - Cerebral ... #Table #Causes ... #Sodium
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Causes of Hypernatremia ... - Differential Diagnosis ... Algorithm Hypernatremia ... water loss, Serum Sodium ... #Algorithm #Causes
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