11 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Urine Na+K / serum ... , Renal Sodium loss ... , Hypervolemia with
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Repeat the sodium ... HYPOVOLEMIC • ... volume loss - diuretics ... EUVOLEMIC • SIADH ... HYPERVOLEMIC • CHF
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
: Diuretics/Nephropathies ... • Euvolemia: SIADH ... Alcohol MH/CCF ... #diagnosis #causes ... #nephrology #sodium
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hypovolemic - Give ... treat underlying cause ... (CHF, cirrhosis ... , SSRIs) - SIADH ... diagnosis #nephrology #sodium
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... water loss, Serum Sodium ... administration • Osmotic diuresis ... • Burns • ICU ... #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Malignancy True hypovolemia ... especially thiazide diuretics ... Reduced GFR, AKI/CRF ... Hypo-osmolar urine
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Malignancy True hypovolemia ... especially thiazide diuretics ... Reduced GFR, AKI/CRF ... Hypo-osmolar urine
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
hypervolemic, hypovolemic ... release of anti-diuretic ... Measured urine sodium ... #RAAS #Hypovolemia ... EBV #potomania #SIADH
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... doses - consider ITU ... • IF SIADH — ... #Management #algorithm ... #treatment #sodium
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Diagnosis Algorithm ... in Cancer UOsm ... 100 mOsm/kg = Urine ... appropriate • Hypovolemia ... inappropriate • SIAD