43 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... disorders • Celiac disease ... effect following treatment ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #hematology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
usually caused by ... Measure urine osmolality ... the underlying cause ... demyelination syndrome ... vaptans (HF/liver disease
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
- Behcet's disease ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #algorithm
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... #Syndrome #Treatment ... #pharmacology #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Differential Diagnosis Algorithm ... Myelodysplastic Syndromes ... • Liver Disease ... #Causes #Hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... 150 published cases ... Relapsing-remitting course +++ Clinical ... hypoalbuminemia with no urine ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology