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Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperuricemia • Acute renal ... Vomiting, decreased urine
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup NAGMA - Chem, ABG or VBG - Calculate Anion
Gap - UAG and Urine ... - Renal • Urine ... Renal Loss of HCO3 ... - Renal insufficiency ... Hypoaldosteronism - Renal
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Haptoglobin Urine ... hemosiderin Urine ... workup #diagnosis #hematology
Renal Tubular Acidosis - Differential Diagnosis Algorithm Decreased Serum K, Urine pH < 5.5 - Proximal RTA Decreased
Renal Tubular Acidosis ... Decreased Serum K, Urine ... Decreased Serum K, Urine ... = Hyperkalemic Renal ... uncimchiefs #RTA #Renal
General approach to AKI - Checklist Urine electrolytes & FENa - Previously, it was believed that urine
- Checklist Urine ... believed that urine ... differentiate between pre-renal ... and intrinsic renal ... Urine eosinophils
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... edema, active urine ... APLA/LAC: • Renal ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
uric acid >4 • Urine ... Na <20: Extra-renal ... losses • Urine ... Na >30: Renal losses ... Na > 30: Renal
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
differential, urine ... dipstick, urine ... urinary sediment, renal ... Myeloma: serum / urine ... blood culture, urine
Hypophosphatemia - Measurement of urine phosphate excretion - Differential Diagnosis Algorithm • GI loss • Redistribution
Measurement of urine ... deficiency • Primary Renal ... Hypophosphatemia #urine
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria: Red/Dark urine ... 1ml blood/liter urine ... more RBC/HPF spun urine ... examination of urine ... #urine #blood
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