1993 results
Evaluation of Secondary Hypertension
 • Primary aldosteronism - PRA, PAC
 • Renal artery stenosis - Renal
- PRA, PAC • Renal ... artery stenosis - Renal ... fT4 • Cushing syndrome ... cortisol. 24-h urine ... Mineralocorticoid excess syndromes
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Na <20: Extra-renal ... losses • Urine ... Na >30: Renal losses ... Cirrhosis, Nephrotic syndrome ... : Renal failure
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
differential, urine ... dipstick, urine ... Abdominal compartment syndrome ... blood culture, urine ... syndrome: troponin
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... , Liddle syndrome
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria: Red/Dark urine ... 1ml blood/liter urine ... disease - Alport syndrome ... pain hematuria syndrome ... • Nutcracker syndrome
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... , Liddle syndrome
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Overfill (Increased renal ... sodium retention, Urine ... • Nephrotic Syndrome ... • Nephrotic syndrome ... Respiratory Distress Syndrome
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Algorithm 1) Check Urine ... mOsm/kg - Implies renal ... , Ingestion Renal ... Hypervolemic: Conn syndrome ... , Cushing syndrome
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
volume contracted: urine ... diuretics after renal ... volume expanded: urine ... contracted: but urine ... generally indicates a renal
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
2-2.5% or 24h Urine ... Malabsorption RENAL ... 2-2.5% or 24h Urine ... • Gitelman's syndrome