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Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... bullae, Ulceration, Urticaria ... - Anti-C1q (Urticarial ... Disease • Cogan syndrome ... #dermatology #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Churg-Strauss syndrome ... hypocomplementary urticarial ... - Schnitzler syndrome ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Hypocomplementemic Urticarial ... - Urticaria and ... : • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... , Purpura, Urticaria ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Hypocomplementemia: Urticarial ... Hypocomplementemic Urticarial ... • Behcet syndrome ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... gangrenosum) • Urticaria ... • Goodpasture syndrome ... Granulomatous vasculitis ... rash #diagnosis #rheumatology
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3)
Hypocomplementemic Urticarial ... Vasculitis (HUV ... HUV 1) Chronic urticaria ... #Vasculitis #HUV ... Diagnosis #Management #Rheumatology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Hypocomplementemic Urticarial ... Vasculitis C1q ... Hypocomplementemic #Urticarial ... #Vasculitis #HUV ... Pathophysiology #Rheumatology
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... Cryoglobulinemic vasculitis ... and Sjogren's syndrome ... • IgA vasculitis ... #vasculitis #differential
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... by large vessel vasculitis ... medium vessel vasculitis ... and small vessel vasculitis ... #Diagnosis #Rheumatology
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